Morning Report: Valproic Acid Toxicity

Today’s Morning Report is presented by Dr. Bart!   Valproic Acid Background -Used for seizure disorders, BPD, migraine prophylaxis. -Peak concentrations at 6 hours except for enteric coated capsules. -Complications: -COMMON: Sedation, ataxia, weight gain, nausea, tremor, or hair loss -SEVERE: Hepatotoxicity, thrombocytopenia, aplastic anemia, pancreatitis, hyperammonemia (>80 ug/dL or Read more…