Morning Report: Organophosphate and Carbamate Poisoning

Today’s Morning Report is presented by Dr. Adal!   Organophosphate and Carbamate Poisoning   Epidemiology: 200K fatalities worldwide every year   DDx: Cholinesterase inhibitors, Cholinomimetics, Nicotine alkaloids   Kinetics: Absorption via ingestion, inhalation or topical contact. Minutes to hours depending on lipophilicity, metabolism and toxicity of compound   Pathophysiology: Inhibition Read more…

Morning Report: Ammonia Toxicity

Dr. Waldman presents today’s Morning Report!   AMMONIA TOXICITY   Where can we find ammonia: glass cleaners, toilet bowel cleaners, metal polishes, floor strippers, wax removers, smelling salts, some refrigerants, explosives, pharmaceuticals, pesticides, textiles, leather, flame-retardants, plastics, pulp and paper, rubber, petroleum products, and cyanide   INHALATION INJURY: Most common Read more…

Morning Report: Procedural Sedation

Dr. Gomes presents today’s Morning Report!   PROCEDURAL SEDATION   Definition: -technique of administering a sedative or dissociative agent along with analgesia to induce a state that allows patient to tolerate unpleasant procedures while maintaining adequate spontaneous cardiorespiratory function   Complications: -oversedation, respiratory depression/arrest, hypoxia, hypotension, prolonged awakening, agitation, nausea/vomiting, Read more…

Morning Report: Valproic Acid Toxicity

Today’s Morning Report is presented by Dr. Bart!   Valproic Acid Background -Used for seizure disorders, BPD, migraine prophylaxis. -Peak concentrations at 6 hours except for enteric coated capsules. -Complications: -COMMON: Sedation, ataxia, weight gain, nausea, tremor, or hair loss -SEVERE: Hepatotoxicity, thrombocytopenia, aplastic anemia, pancreatitis, hyperammonemia (>80 ug/dL or Read more…