D-dimer for aortic dissection screening: is it ADvISEDable? A (relatively) brief lit review

Introduction As far as dangerous causes of chest pain go, acute aortic syndromes (aortic dissection, intramural thrombus, and penetrating aortic ulcer) can present a real diagnostic dilemma. They’re rare (with a prevalence of around 2-4 per 100,000 individuals), seem to present in a myriad of ways, and are invariably life-threatening. Read more…