D-dimer for aortic dissection screening: is it ADvISEDable? A (relatively) brief lit review

Introduction As far as dangerous causes of chest pain go, acute aortic syndromes (aortic dissection, intramural thrombus, and penetrating aortic ulcer) can present a real diagnostic dilemma. They’re rare (with a prevalence of around 2-4 per 100,000 individuals), seem to present in a myriad of ways, and are invariably life-threatening. Read more…

PE Prevalence in ED Patients Presenting with Syncope (Part 1)

What is the prevalence of PE in patients who present to the ED with syncope? References 1. Prandoni P, Lensing AWA, Prins MH, et al. Prevalence of Pulmonary Embolism among Patients Hospitalized for Syncope. N Engl J Med [Internet]2016;375(16):1524–31. Available from: https://doi.org/10.1056/NEJMoa1602172 2. Oqab Z, Ganshorn H, Sheldon R. Prevalence Read more…

Can experienced clinician gestalt + ECG accurately exclude acute MI?

Last month Academic Emergency Medicine published the article “Can emergency physician gestalt ‘rule in’ or ‘rule out’ acute coronary syndrome: validation in a multi-center prospective diagnostic cohort study”. The following is a critique by Dr. deSouza and Dr. Sinert: In this large multi-center, prospective diagnostic accuracy study, the investigators conclude Read more…

Cardioversion for Recent-Onset Atrial Fibrillation: Early, Delayed, or Not at All?

A recent NEJM article, “Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation” by Pluymaekers et al has reinvigorated debate in the blogosphere, academia conference halls, and podcast-dom over management of recent-onset atrial fibrillation (AF) (1,2,3). Prior studies have demonstrated that cardioversion for recent-onset atrial fibrillation (typically defined by a duration Read more…