Pharmacology

The PROCAMIO Study – Procainamide or Amiodarone for Stable Wide QRS Tachycardia

Background 2017 AHA/ACC guidelines for the treatment of hemodynamically stable patients with ventricular tachycardia (VT) include the following recommendations:1 Intravenous procainamide can be useful to terminate VT. (Class IIa) Intravenous amiodarone or sotalol may be considered to terminate VT. (Class IIb) In 2013, deSouza et al conducted a systematic literature Read more…

By Stacey Frisch, ago

Xigris: The drug that cured sepsis… but then actually didn’t

In 2001, the only drug to treat sepsis was approved by the FDA and swiftly brought to market by Eli Lilly & Co. So, why have most residents never heard of Xigris (drotrecogin alfa)?                                                                                                                                                                                                             By Dr. Lee Grodin   [1] Bloomberg News. Lilly Read more…

By kkelson, ago