Immune/Inflammatory

Toxic shock-like syndrome and COVID-19: A case report of multisystem inflammatory syndrome in children (MIS-C)

This article is reposted from The American Journal of Emergency Medicine.  Introduction The coronavirus disease 2019 (COVID-19) pandemic has caused a total of nearly 300,000 deaths worldwide [1]. Pediatric patients PCR-postive for SARS-CoV-2 present differently than adults with 40% either asymptomatic or with URI symptoms and commonly have pharyngeal erythema Read more…

By Andrea Greene, ago

Wednesday Wrap-up 11/28 – Anaphylaxis, AV Node Blocks and Cardiotoxic Drugs

For those who were not in conference yesterday: Dr. Rushabh Shah discussed AV nodal blocks: For all AV blocks consider: beta blocker or calcium channel blocker overdose, hyperkalemia, inferior MI, cardiomyopathy, and myocarditis 1st degree and 2nd degree Mobitz type 1 AV block: typically benign 2nd degree Mobitz type 2: Read more…

By Charles Murchison, ago

Xigris: The drug that cured sepsis… but then actually didn’t

In 2001, the only drug to treat sepsis was approved by the FDA and swiftly brought to market by Eli Lilly & Co. So, why have most residents never heard of Xigris (drotrecogin alfa)?                                                                                                                                                                                                             By Dr. Lee Grodin   [1] Bloomberg News. Lilly Read more…

By kkelson, ago