Does Observation for ACS Makes Sense? Part 1: A History of Observation for Chest Pain

Accurate and expeditious diagnosis of acute myocardial infarction or acute coronary syndrome (ACS) is one of the key charges of emergency medicine providers. Chest pain is the second most common reason for emergency department visits in the United States and coronary artery disease is our leading cause of death (1,2). Read more…

Can a lower dose of acetazolamide prevent acute mountain sickness?

The RADICAL Trial was a prospective, double-blind, randomized, non-inferiority trial evaluating reduced dose (62.5 mg twice daily) vs. standard dose (125 mg twice daily) of acetazolamide for the prevention of acute mountain sickness in adults trekking to Everest Base Camp in Nepal.(1). Background: The current standard pharmacologic prophylaxis for acute Read more…