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Toxicology

Up to date review and in depth analysis of Emergency Medicine toxicology topics

EM-Critical Care Toxicology

Carbon Monoxide and Cyanide Poisoning

EM-CCM Conference 1/21/15 Fire Exposure/Injuries Presented by:  Dr. Danica Gomes Summary by:  Dr. Kaycie Corburn The Case:  60 yo F unknown PMH BIBEMS from a house fire.  There were known fatalities at this house fire.  The patient was being ventilated by EMS personnel via BVM on arrival.  Triage vitals revealed Read more…

By sbogoch, 10 yearsFebruary 1, 2015 ago
Toxicology

Differential Diagnosis of Hypotension and Bradycardia in the Poisoned Patient

Welcome to the Kings County/SUNY Downstate toxicology blog series. In our first case, we will discuss the differential diagnosis and management of the poisoned patient who presents with hypotension and bradycardia. Case A 23 year old female is brought in by EMS after an intentional overdose. She reports taking a Read more…

By nathan, 10 yearsDecember 25, 2014 ago
Toxicology

Nebulized Naloxone

Weber, et al. Prehosp Emerg Care, 2mg naloxone nebulized with 3mL normal saline 105 cases- 22% complete response, 59% partial response, 19% no response No adverse events, no intubations or BVM ventilations Only 10% were given a second dose of naloxone Unclear how response was determined (likely subjective) Baumann et Read more…

By Jay Khadpe MD, 10 yearsDecember 23, 2014 ago
Toxicology

Ackee Fruit Toxicity

Ackee fruit grows mostly in the Caribbean islands and West Africa. The unripe fruit contains hypoglycin A. A metabolite of hypoglycin A binds to carnitine and coenzyme A, making them unavailable for metabolic reactions. Lack of these enzymes leads to inability to perform gluconeogenesis. When ackee fruit is allowed to Read more…

By Jay Khadpe MD, 11 yearsSeptember 4, 2014 ago
Toxicology

Gamma-Butyrolactone (GBL) Toxicity

Gamma-Butyrolactone (GBL) is an addictive depressant used for its euphoric and sleep inducing effects. It is a prodrug to GHB. GBL can be synthesized from gamma-hydroxybutyric acid (GHB) by removal of water or by distillation from such a mixture.   Pathophysiology: GBL readily crosses the blood-brain barrier with rapid onset Read more…

By Jay Khadpe MD, 11 yearsAugust 14, 2014 ago
Toxicology

Lipid Resuscitation Therapy

Dr. Aluisio presents today’s Morning Report!

By Jay Khadpe MD, 11 yearsMay 2, 2014 ago
EM-Critical Care Toxicology

Beta-Blocker Toxicity

EM CCM Conference: October 2013 BETA-BLOCKER TOXICITY PRESENTED BY DR. KENDALL SUMMARY BY DR. YOUN The Case: HISTORY: 91F with HTN, DM on carvedilol, labetalol BIBEMS for weakness, dizziness, and near-syncope.   VITALS: BP 76/38, HR 41   PRIMARY INTERVENTIONS: Intubation, fluids, atropine, dopamine drip, pacer pads applied   PHYSICAL:, Read more…

By Jay Khadpe MD, 11 yearsNovember 13, 2013 ago

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Search the Site
Welcome to the official blog of the Kings County/SUNY Downstate Emergency Medicine Residency!

We are the residents (and some attendings) of the Kings County Hospital Emergency Department who have put together a unique mostly resident-authored blog for medical professionals.

If you have ideas for a post or are just looking for a fun way to do some individualized learning, e-mail us at CountyEMBlog@gmail.com and come be a part of our team!

Visit our YouTube channel for our recorded monthly conference lectures
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Before you Walk in the Room: Abnormal Uterine Blee
Before you Walk in the Room: Abnormal Uterine Bleeding 
Is your patient presenting with abnormal uterine bleeding? Use the mnemonic PALM-COEIN to quickly formulate a differential before you walk in the room.
#emergency #emergencymedicine #medicalstudent #emresident #resident #intern #ms4 #ms3 #foamed #awayrotation #subi #differential #mnemonic #step1 #step #step3


County EM presents a case of an 18 year old male B
County EM presents a case of an 18 year old male BIBEMS after being found collapsed during a half marathon. He is obtunded, diaphoretic, tachycardic, tachypneic, and has a rectal temp of 107F.
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Exertional Heat Stroke

Take Home Points:

1. Though there are no head-to-head comparisons, cold water immersion appears to be the most effective method of rapid cooling

2. Consider placing defibrillator pads before water immersion

3. Consider the use of a body bag for rapid initiation of cold water immersion

4. Employ an ‘all hands on deck’ strategy to obtain ice from the nearest source

Check out our story and highlight reel for direct links to the article! Also check out our website for more juicy content!


Morning Report Recap- Dr. Natassia Buckridge on Ke
Morning Report Recap- Dr. Natassia Buckridge on Ketamine vs PNB for analgesia


Before you Walk in the Room: Headaches
The key to

Before you Walk in the Room: Headaches
The key to tackling headaches? Knowing primary from secondary. 
#emergency #headache #migraine #emergencymedicine #em #emresident #medicalstudent #ms4 #ms3 #awayrotation #rotations #subi #diagnosis #foamed #step1 #step2 #step3


BYWITR: Joint Pain
Is your patient presenting with

BYWITR: Joint Pain
Is your patient presenting with joint pain? Think arthritis. Here's a way you can formulate a differential diagnosis before you walk into the room.
#emergency #emergencymedicine #medicalstudent #emresident #resident #intern #ms4 #ms3 #foamed #awayrotation #subi #differential


Slit lamp mechanics with our very own Dr. Silverbe
Slit lamp mechanics with our very own Dr. Silverberg!


Before You Walk In The Room: Eye Pain
Going to see

Before You Walk In The Room: Eye Pain
Going to see a patient with a painful eye? remember to take an anatomical approach!
#emergency #emergencymedicine #medicalstudent #emresident #resident #intern #ms4 #ms3 #foamed #awayrotation #subi #differential


County EM presents a case of an 18 year old male B
County EM presents a case of an 18 year old male BIBEMS after being found collapsed during a half marathon. He is obtunded, diaphoretic, tachycardic, tachypneic, and has a rectal temp of 107F.
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Exertional Heat Stroke

Take Home Points:

1. Exertional heat stroke is a time-sensitive diagnosis.

2. The core body temperature threshold of > 40 degrees Celsius may be inaccurate.  More attention should be focused on pathological symptoms in the right clinical context.

3. Anticipate common complications including thrombocytopenia, coagulopathy, liver damage, acute kidney injury, lactic acidosis, cardiovascular dysfunction, and rhabdomyolysis.

Check out our story and highlight reel for direct links to the article! Also check out our website for more juicy content!


Before you Walk in the Room: Sinus Tachycardia
He

Before you Walk in the Room: Sinus Tachycardia 
Heart rate not going down? Looking for the cause? 
Use the mnemonic "FHAST PACED" to quickly identify potential causes of tachycardia in your patient. 
#emergency #emergencymedicine #medicalstudent #emresident #resident #intern #ms4 #ms3 #foamed #awayrotation #subi #differential


H2H: De Winters Pattern: An OMI Equivalent for Pro
H2H: De Winters Pattern: An OMI Equivalent for Proximal LAD Occlusion
#emergency #emergencymedicine #medicalstudent #emresident #resident #intern #ms4 #ms3 #foamed #awayrotation #subi #differential #mnemonic


BYWITR: Syncope
Picked up a patient with syncope?

BYWITR: Syncope
Picked up a patient with syncope? Use this framework to formulate a differential before you walk in the room 
#emergency #emergencymedicine #medicalstudent #emresident #resident #intern #ms4 #ms3 #foamed #awayrotation #subi #differential


County EM presents a case of a 40-year-old woman w
County EM presents a case of a 40-year-old woman with a history of CAD and prior RCA stent who arrives to the ED with chest pain for one day. Her triage vitals are within normal limits but you notice the patient holding her chest in pain with diaphoresis. Besides ECG and blood work, what else can be used to risk stratify the patient for ACS?
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TTE for Regional Wall Motion Abnormalities

Take Home Points:

1. Regional wall motion abnormalities occur early, before ECG changes or pain

2. Consider TTE if ECG is non-diagnostic for OMI, especially in patients with moderate to high likelihood of OMI

3. Look at a prior TTE, if available

4. Know the “false-positive” causes of regional wall motion abnormalities

5. Learn the coronary anatomy to correlate with regional wall motion abnormalities

Check out our story and highlight reel for direct links to the article! Also check out our website for more juicy content!


Welcome to our Before you Walk in the Room series-
Welcome to our Before you Walk in the Room series-
Altered mental status
Is your patient confused or acting out of character? Identify the cause with AEIOU-TIPS, a mnemonic for altered mental states
#emergencymedicine #residency #medicalstudent #meded #foamed #intern #ms4 #ms3 #mnemonics


Welcome back to part 3 of Hypertrophic Cardiomyopa
Welcome back to part 3 of Hypertrophic Cardiomyopathy!
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Take Home Points:

1. When patients with known or suspected HCM present hypotensive, maximize preload and afterload and avoid inotropes and chronotropes as they may worsen LVOTO.

2. Patients with HCM can have poor tolerance to atrial fibrillation and rhythm control strategy with cardioversion or antidysrhythmics drugs should be considered.

3. First-line treatment to prevent recurrent of ventricular dysrhythmias in HCM patients are beta-blockers.

4. ICD placement in patients with HCM has been shown to reduce mortality and is a class 1 recommendation in those with an episode of SCD in the past, ventricular fibrillation, or sustained ventricular tachycardia. Remember to ask about SCD risk factors such as family history of SCD or unexplained syncope. 

5. Patients with symptoms should be admitted while those that are  asymptomatic with known or suspected HCM can follow up with cardiology on an out-patient basis.

Check out our story and highlight reel for direct links to the article! Also check out our website for more juicy content!


Welcome to "Did You Ask?" a segment where we talk
Welcome to "Did You Ask?" a segment where we talk about important pieces of information that you need to get on history when examining patients. 
Today we're gonna be talking about back pain one of the most common chief complaints in the ED. 
#emergency #emergencymedicine #medicalstudent #emresident #resident #intern #ms4 #ms3 #foamed #awayrotation #subi #differential #mnemonic #backpain #step1 #step2 #step3 #ms1 #ms2


Welcome back to part 2 of Hypertrophic Cardiomyopa
Welcome back to part 2 of Hypertrophic Cardiomyopathy!
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Take Home Points:

1. Ask about chest pain, shortness of breath, palpitations, and/or syncope on exertion during your interview 

2. ECG findings are not diagnostic but classic findings include LVH, pathologic ‘dagger’ Q waves, deep S waves in V1-V3, and high R wave in V4-V6 with abnormal T waves 

3. A bedside parasternal short axis view with an end-diastole wall thickness ≥ 15 mm is highly suspicious for HCM and warrants further investigation 

4. Beta blockers are first line pharmacological intervention and in those with refractory symptoms consider disopyramide or surgical intervention via myomectomy or alcohol septal reduction

Stay tuned for part 3 as we discuss treatment of emergent conditions and prevention of SCD!

Check out our story and highlight reel for direct links to the article! Also check out our website for more juicy content!


Heart 2 Heart
Identifying Wellen's Syndrome- Keep

Heart 2 Heart 
Identifying Wellen's Syndrome- Keep an eye out for reperfusion T waves in the inferior or lateral leads if you have transient reperfusion of the RCA or LCx- the same pattern can happen in any of the coronary distributions!


County EM presents a case of a 59-year-old male wi
County EM presents a case of a 59-year-old male with a past medical history of hypertension, hyperlipidemia, and gastroesophageal reflux disease was brought in by EMS to the ED with severe chest pain
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Hypertrophic Cardiomyopathy (HCM)

Take Home Points:

1. HCM includes a complex interplay of left ventricular outflow tract obstruction (LVOTO), mitral regurgitation, diastolic dysfunction, myocardial ischemia, arrhythmias, and autonomic dysfunction

2. Although classically thought of as septal hypertrophy leading to LVOTO, multiple variants have been identified. Variants including concentric, reverse septal, neutral, and apical HCM have been identified, and nearly any pattern of LV wall thickening can occur with HCM.

3. Common adverse events include sudden cardiac death, symptoms of left ventricular outflow tract obstruction, heart failure, and arrhythmias 

4. Patients with HCM are at higher risk for myocardial ischemia even in the absence of CAD. 

5. The pathophysiology of anginal chest pain and rising troponin in HCM is related to increased oxygen demand secondary to hypertrophy, microvascular dysfunction, and small coronary vessel medial hypertrophy, which causes decreased coronary flow reserve and regional myocardial ischemia. 

Stay tuned for part 2 as we discuss early identification of HCM!!

Check out our story and highlight reel for direct links to the article! Also check out our website for more juicy content!


Today we share a post on the pathophysiology and m
Today we share a post on the pathophysiology and management of priapism. The big takeways are as follows:

1) Priapism is  either ischemic or non-ischemic and this is one of the most important distinctions to make as untreated ischemic priapism leads to fibrosis and permant sexual dysfunction.

2. Cavernosal blood gas in ischemic priapism will show elevated PaCO2 > 60 mmHg, decreased PaO2 < 30 mmHg, and pH < 7.25.

3. The most important treatment for priapism is drainage. This is achieved by injecting a 20-gauge needle into the 3 o'clock or 9 o'clock (sometimes both) position to aspirate blood from the corpus cavernosum. It is important to only aspirate from these positions to avoid injury to dorsal vessels or the urethra.

4. Once drainage is complete, inject phenylephrine into the corpus cavernosum to help prevent re-accumulation.

5. Most pharmacies will give you a phenylephrine bottle with 10 mg/mL concentration. You should dilute this ten-fold: take 1 mL of phenylephrine and mix into a 9 mL saline flush, creating a new concentration of 1mg/mL, or 1000 mcg/mL. You can inject 0.5cc of your phenylephrine mixture into the corpus cavernosa using the same needle you used for drainage (limit to 3 injections).

6. Lastly, all patients with priapism should be scheduled for urgent urology follow-up. For patients with recurrent episodes, or where multiple attempts at drainage have proven unsuccessful, you can consider an emergent urology consult.

Check out our story and highlight reel for direct links to the article! Also check out our website for more juicy content!


Today we share a post on the management of intracr
Today we share a post on the management of intracranial hemorrhage. The goal in the ED is to prevent hematoma expansion, edema, and herniation. The big takeaways are as follows:

1. For patients presenting with systolic blood pressure (SBP) between 150 and 220 mmHg, acute lowering of SBP to a target of 130 to 150 mmHg is safe and reasonable 

2. Seizure prophylaxis is not routinely recommended except in lobar involvement.

3. Studies show that hypertonic saline leads to a greater reduction in ICP when compared to mannitol.

Check out our story and highlight reel for direct links to the article! Also, check out our website for more juicy content!



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