Author: Jonathan McMahon, DO, MA Edited by: Robert Allen, MD; Noah Berland, MD Tranexamic Acid (TXA) has been in the literature a lot recently. Between the HALT-IT trial for its use in GI bleed, CRASH-2 and MATTERs for its use in trauma victims, WOMAN for TXA for postpartum hemorrhage, CRASH-3 Read more…
Episode recap: When last we left our hero, known throughout the globe as Clotting Wonder, it was after a grueling battle with traumatic intracranial hemorrhage. Having been put to the test by post-partum hemorrhage in the WOMAN trial, our hero vanquished the evil villain of traumatic hemorrhage (in the exhilarating Read more…
By Yanmen Yang, PharmD What is tranexamic acid? Tranexamic acid (TXA) is an antifibrinolytic agent approved by the Food and Drug Administration in December 1996 as an intravenous injection to reduce hemorrhage during tooth extractions and as an oral tablet in November 2009 for heavy menstrual cycles.1,2 Since then, Read more…
Tranexamic acid (TXA) is an antifibrinolytic drug that was first discovered nearly 60 years ago by two Japanese scientists. TXA has been used to mitigate blood loss in elective surgeries, hemophiliacs, post-partum hemorrhage, and most recently after major trauma1. Here in the Kings County blogosphere, we review the use of TXA for Read more…